6fqm_ABCD : 3D-footprint complex

structure name	3.06A COMPLEX OF S.AUREUS GYRASE WITH IMIDAZOPYRAZINONE T1 AND DNA
reference	Maxwell et al. 'Nucleic 46 4114 2018
source	STAPHYLOCOCCUS AUREUS SUBSP. AUREUS N315
experiment	X-ray (resolution=3.06, R-factor=?)
structural superfamily	Type II DNA topoisomerase;
reference complex	5iwi_C 5iwi_D
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6fqm_A interface=76,77,114,166, inernitsemresfldyamsvivaralpdvrdglkpvhrrilyglneqgmtpdksykksarivgdvmgkyhphgdSSiyeamvrmaqdfsyryplvdgqgnfgsmdgdgaaamRtearmtkitlellrdinkdtidfidnydgnerepsvlparfpnllangasgIavgmatnipphnltelingvlslsknpdisiaelmediegpdfptaglilgksgirrayetgrgsiqmrsravieergggrqrivvteipfqvnkarmiekiaelvrdkkidgitdlrdetslrtgvrvvidvrkdanasvilnnlykqtplqtsfgvnmialvngrpklinlkealvhylehqktvvrrrtqynlrkakdrahileglrialdhideiistiresdtdkvameslqqrfklsekqaqaildmrlrrltglerdkieaeynellnyiseletiladeevllqlvrdelteirdrfgddrrteiql > 6fqm_B interface=31, dcskspeeceiflvegdsgrrtqailplrgKilnvekarldrilnnneirqmitafgtgiggdfdlakaryhkivimtdadvdgahirtllltffyrfmrplieagyvyiaqpttmnpeallqvkledaieadqtfemlmgdvvenrrqfiednav > 6fqm_C interface=75,76,79,113,165, nernitsemresfldyamsvivaralpdvrdglkpvhrrilyglneqgmtpdksykksarivgdvmgkyhphgdSSiyEamvrmaqdfsyryplvdgqgnfgsmdgdgaaamRtearmtkitlellrdinkdtidfidnydgnerepsvlparfpnllangasgIavgmatnipphnltelingvlslsknpdisiaelmediegpdfptaglilgksgirrayetgrgsiqmrsravieergggrqrivvteipfqvnkarmiekiaelvrdkkidgitdlrdetslrtgvrvvidvrkdanasvilnnlykqtplqtsfgvnmialvngrpklinlkealvhylehqktvvrrrtqynlrkakdrahileglrialdhideiistiresdtdkvameslqqrfklsekqaqaildmrlrrltglerdkieaeynellnyiseletiladeevllqlvrdelteirdrfgddrrteiql > 6fqm_D interface=25, speceiflvegddsrtqailplrgKilnvekarldrilnnneirqmitafgtgiggdfdlakaryhkivimtdadvdgahirtllltffyrfmrplieagyvyiaqpllwettrallqvkledaieadqtfemlmgdvvenrrqfiedna
interface signature	SSRI/K/SSERI/K

Estimated binding specificities ?

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# IC=9.592 IC/col=0.685 n_of_columns=14

specificity:

A |  96   0  24  84  11   6  24  24   3  81   3  24   0   0
C |   0   0  24   3  14   3  24  24  73   7   3  24  96   0
G |   0  96  24   6  11  84  24  24   6   3   6  24   0   0
T |   0   0  24   3  60   3  24  24  14   5  84  24   0  96

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updated Tue Sep 10 13:24:08 2024