6fqq_AB : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF TALE HOMEOBOX DOMAIN TRANSCRIPTION FACTOR TGIF1 DOUBLE ALANINE MUTANT BOUND TO ITS CONSENSUS DNA
reference	Macias et al. 'Nucleic 46 9220 2018
source	Homo sapiens
experiment	X-ray (resolution=3.25, R-factor=?)
structural superfamily	Homeodomain-like;
reference complex	6fqp_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6fqq_A interface=44,47,48,51,52, nlpkesvqilrdwlyehrynaypseqekallsqqthlstlqvcNwfINarRRllpdmlrk > 6fqq_B interface=45,48,49,52,53, gnlpkesvqilrdwlyehrynaypseqekallsqqthlstlqvcNwfINarRRllpdmlrk
interface signature	NINRR/NINRR

Estimated binding specificities ?

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# IC=11.553 IC/col=0.963 n_of_columns=12

specificity:

A |   6   0  96   0  68  20  24   0   0   0   0  96
C |  16   0   0  96  13  13  24   0   0   6  96   0
G |  13  96   0   0   9  57  24   0  96   0   0   0
T |  61   0   0   0   6   6  24  96   0  90   0   0

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updated Tue Jan 6 04:04:50 2026