6fqq_DE : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF TALE HOMEOBOX DOMAIN TRANSCRIPTION FACTOR TGIF1 DOUBLE ALANINE MUTANT BOUND TO ITS CONSENSUS DNA
reference	Macias et al. 'Nucleic 46 9220 2018
source	Homo sapiens
experiment	X-ray (resolution=3.25, R-factor=?)
structural superfamily	Homeodomain-like;
reference complex	6fqq_E
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6fqq_D interface=47,50,51,54,55, aagnlpkesvqilrdwlyehrynaypseqekallsqqthlstlqvcNwfINarRRllpdmlrk > 6fqq_E interface=45,48,49,52,53, gnlpkesvqilrdwlyehrynaypseqekallsqqthlstlqvcNwfINarRRllpdmlrk
interface signature	NINRR/NINRR

Estimated binding specificities ?

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# IC=11.638 IC/col=0.970 n_of_columns=12

specificity:

A |   3   0  65  20  96   6  10   0   0   0   0  77
C |   6   0  30  58   0  10  77   0   0   0  96   6
G |   9  96   1   6   0  74   6   0  96   0   0   3
T |  78   0   0  12   0   6   3  96   0  96   0  10

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updated Thu Jun 25 15:07:10 2026