6fzs_AB : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF SMAD5-MH1 BOUND TO THE GGCGC SITE.
reference	Kaczmarska et al. 'Computational 19 ? 2021
source	Homo sapiens
experiment	X-ray (resolution=2.31, R-factor=?)
structural superfamily	SMAD MH1 domain;
reference complex	6fzs_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6fzs_A interface=64,66,68,73, ftspavkrllgwkqgdeeekwaekavdalvkklkkkkgameelekalsspgqpskcvtiprslDgRlQvshrKglphviycrvwrwpdlqshhelkpldicefpfgskqkevcinpyhykrvesp > 6fzs_B interface=64,66,68,73, ftspavkrllgwkqgdeeekwaekavdalvkklkkkkgameelekalsspgqpskcvtiprslDgRlQvshrKglphviycrvwrwpdlqshhelkpldicefpfgskqkevcinpyhykrvespvl
interface signature	DRQK/DRQK

Estimated binding specificities ?

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# IC=10.523 IC/col=1.052 n_of_columns=10

specificity:

A |  72   0   8   0   0   0   0   0   0   8
C |   8   0  16  96   0  96   0  96  96   8
G |   8  96  16   0  96   0  96   0   0  16
T |   8   0  56   0   0   0   0   0   0  64

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updated Thu Jun 25 15:10:11 2026