interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF NME2CAS9 IN COMPLEX WITH SGRNA AND TARGET DNA (AGGCCC PAM)
(CRISPR-associated endonuclease Cas9)
referenceCheng et al. Mol.Cell 76 938 2019
sourceNeisseria meningitidis
experimentX-ray (resolution=3.20, R-factor=0.254)
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKDSNRYT

Estimated binding specificities ?

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# IC=3.520 IC/col=0.880 n_of_columns=4 specificity:   
A |   0  19   0  19
C |   0  20   0   1
G |   0  38  96  76
T |  96  19   0   0
scan!

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updated Tue Dec 17 04:35:12 2024