interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF DCAS9 IN COMPLEX WITH SGRNA AND DNA (TGA PAM)
(CRISPR-associated endonuclease Cas9)
referenceZhang et al. 'Plos 17 e3000496 2019
sourceStreptococcus pyogenes serotype M1
experimentX-ray (resolution=3.20, R-factor=0.201)
multimeric complexes7v59_BE
reference complex6vpc_F
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKERR

Estimated binding specificities ?

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# IC=2.433 IC/col=0.608 n_of_columns=4 specificity:   
A |  42   7   0  67
C |  18   7  96   9
G |  18   8   0   9
T |  18  74   0  11
scan!

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updated Fri Jan 9 07:14:00 2026