interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF XCAS9 IN COMPLEX WITH SGRNA AND DNA (TGC PAM)
(CRISPR-associated endonuclease Cas9Csn1)
referenceZhang et al. 'Plos 17 e3000496 2019
sourceStreptococcus pyogenes serotype M1
experimentX-ray (resolution=3.01, R-factor=0.239)
multimeric complexes7v59_BE
reference complex6vpc_F
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKRR

Estimated binding specificities ?

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# IC=4.007 IC/col=0.801 n_of_columns=5 specificity:   
A |   9  67   9   0  96
C |  11  11   9  96   0
G |   9   9  69   0   0
T |  67   9   9   0   0
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updated Fri Jan 9 07:15:28 2026