6l6l_AB : 3D-footprint complex

structure name	STRUCTURAL BASIS OF NR4A2 HOMODIMERS BINDING TO SELECTIVE NUR- RESPONSIVE ELEMENTS
reference	Jiang et al. J.Biol.Chem. 294 19795 2019
source	HOMO SAPIENS
experiment	X-ray (resolution=2.78, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
reference complex	6l6q_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6l6l_A interface=11,20,23,27,28,81, lcavcgdnaaCqhygvrtcEgcKgffKRtvqknakyvclankncpvdkrrrnrcqycrfqkclavgmvkevvrtdslkgrRgrlp > 6l6l_B interface=11,20,23,27,28,81,83, lcavcgdnaaCqhygvrtcEgcKgffKRtvqknakyvclankncpvdkrrrnrcqycrfqkclavgmvkevvrtdslkgrRgRl
interface signature	CEKKRR/CEKKRRR

Estimated binding specificities ?

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# IC=10.290 IC/col=0.572 n_of_columns=18

specificity:

A |   7  24   0   0  24   0  73  24  24  24  24  24   7   0  24   0   0   7
C |   9  24   0   0  24  96   7  24  24  24  24  24   7   0  24  96  96   7
G |   7  24  96  96  24   0   9  24  24  24  24  24   7  96  24   0   0   9
T |  73  24   0   0  24   0   7  24  24  24  24  24  75   0  24   0   0  73

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updated Sat Dec 14 15:32:50 2024