6l6q_B : 3D-footprint complex

structure name	STRUCTURAL BASIS OF NR4A2 HOMODIMERS BINDING TO SELECTIVE NUR- RESPONSIVE ELEMENTS (NUCLEAR RECEPTOR RELATED 1)
reference	Jiang et al. J.Biol.Chem. 294 19795 2019
source	HOMO SAPIENS
experiment	X-ray (resolution=2.60, R-factor=0.255)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
sequence family	Zinc finger, C4 type two domains;
multimeric complexes	6l6l_AB 6l6q_AB
redundant complexes	6l6l_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6l6q_B interface=11,20,23,27,28,81,83, lcavcgdnaaCqhygvrtcEgcKgffKRtvqknakyvclankncpvdkrrrnrcqycrfqkclavgmvkevvrtdslkgrRgRlp
interface signature	CEKKRRR

Estimated binding specificities ?

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# IC=6.338 IC/col=0.704 n_of_columns=9

specificity:

A |   7   7  75   0   0   0  24  24  75
C |   9   9   7  96  96   0  24  24   7
G |   7  73   7   0   0   0  24  24   7
T |  73   7   7   0   0  96  24  24   7

scan!

Dendrogram of similar interfaces ?

matrix format

  
  CAECKG--KGRG--RTRT   L                          +---1cit_A    
                                    +-------------2 
  --EAKG--KTRG------   L        +---3             +---4umm_A    
                                !   ! 
  ----KGVT--RG------   L   +----4   +-----------------2c7a_B    
                           !    ! 
  --ECKGAG--RG------   L --5    +---------------------4ond_A    
                           ! 
  --ECKGAGKGRG------   L   !                         +1hcq_E    
                           +-------------------------1 
  --ECKGAG--KTRG----   L                             +4aa6_B

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updated Sat Jan 10 10:54:52 2026