interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF FOXO1-DBD HOMODIMER BOUND TO A PALINDROMIC DNA SEQUENCE
referenceChen et al. 'Nucleic 49 3573 2021
sourceHOMO SAPIENS
experimentX-ray (resolution=3.07, R-factor=?)
structural superfamily"Winged helix" DNA-binding domain;
reference complex4lg0_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureNSRHS/SNSRHS

Estimated binding specificities ?

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# IC=11.879 IC/col=0.990 n_of_columns=12 specificity:   
A |   0  96  96  69   8  88   0  24   8   0   0  96
C |   0   0   0  11  72   8   0  24  11   0   0   0
G |   0   0   0   8   8   0   0  24   8   0   0   0
T |  96   0   0   8   8   0  96  24  69  96  96   0
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updated Tue Jan 6 07:52:33 2026