interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF FOXO1-DBD HOMODIMER BOUND TO A PALINDROMIC DNA SEQUENCE
referenceChen et al. 'Nucleic 49 3573 2021
sourceHOMO SAPIENS
experimentX-ray (resolution=3.07, R-factor=?)
structural superfamily"Winged helix" DNA-binding domain;
reference complex4lg0_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureNSRHS/NSRHSL

Estimated binding specificities ?

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# IC=10.745 IC/col=0.895 n_of_columns=12 specificity:   
A |   2  90  96  54   1  93   0  24  13   0   1  96
C |   1   1   0  15  67   1   0  24  18   0   1   0
G |   1   4   0  14  15   1   0  24  11   0   4   0
T |  92   1   0  13  13   1  96  24  54  96  90   0
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updated Tue Jan 6 07:52:43 2026