interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF FOXO1-DBD HOMODIMER BOUND TO A PALINDROMIC DNA SEQUENCE
referenceChen et al. 'Nucleic 49 3573 2021
sourceHOMO SAPIENS
experimentX-ray (resolution=3.07, R-factor=?)
structural superfamily"Winged helix" DNA-binding domain;
reference complex3co6_C
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureNSRHS/NSRHSL

Estimated binding specificities ?

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# IC=10.867 IC/col=0.906 n_of_columns=12 specificity:   
A |   0  87  96  61  24  93   2   5   5   0   2  87
C |   0   2   0  11  24   3   2   2  14   0   5   5
G |   0   5   0  16  24   0   2  87  11   0   2   2
T |  96   2   0   8  24   0  90   2  66  96  87   2
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updated Tue Sep 10 16:27:18 2024