6lbi_GH : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF FOXO1-DBD HOMODIMER BOUND TO A PALINDROMIC DNA SEQUENCE
reference	Chen et al. 'Nucleic 49 3573 2021
source	HOMO SAPIENS
experiment	X-ray (resolution=3.07, R-factor=?)
structural superfamily	"Winged helix" DNA-binding domain;
reference complex	3co6_C
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6lbi_G interface=54,55,57,58,61, nawgnlsyadlitkaiessaekrltlsqiyewmvksvpyfkdkgdsnssagwkNSiRHnlSlhskfirvqnegtgksswwmln > 6lbi_H interface=48,49,51,52,55,56, nawgsyadlitkaiessaekrltlsqiyewmvksvpyfkdkgdagwkNSiRHnlSLhskfirvqneksswwmln
interface signature	NSRHS/NSRHSL

Estimated binding specificities ?

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# IC=10.988 IC/col=0.916 n_of_columns=12

specificity:

A |   0  96  96  52  24  96   2   2  13   0   2  90
C |   0   0   0  19  24   0   2   2  17   0   5   2
G |   0   0   0  14  24   0   5  87  14   0   2   2
T |  96   0   0  11  24   0  87   5  52  96  87   2

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updated Wed Jul 30 21:15:05 2025