6lc1_AD : 3D-footprint complex

structure name	STRUCTURAL BASIS OF NR4A1 BOUND TO THE HUMAN PITUITARY PROOPIOMELANOCORTIN GENE PROMOTER
reference	Jiang et al. Biochem.Biophys.Res.Commun. 523 1 2020
source	HOMO SAPIENS
experiment	X-ray (resolution=3.12, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
reference complex	6l6q_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6lc1_A interface=11,14,20,23,27,28,81,83, rcavcgdnasCqhYgvrtcEgcKgffKRtvqknakyiclankdcpvdkrrrnrcqfcrfqkclavgmvkevvrtdslkgrRgRlps > 6lc1_D interface=12,15,21,24,28,29,82,84, grcavcgdnasCqhYgvrtcEgcKgffKRtvqknakyiclankdcpvdkrrrnrcqfcrfqkclavgmvkevvrtdslkgrRgRlp
interface signature	CYEKKRRR/CYEKKRRR

Estimated binding specificities ?

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# IC=14.969 IC/col=0.680 n_of_columns=22

specificity:

A |   3   0  24   0  96   3  24   3   5  24  24  24  12   3  24  24  85   0  96  24   0  85
C |   3   0  24  96   0   5  24   3   3  24  24  24   6   3  24  24   3   0   0  24  96   5
G |   3  96  24   0   0   3  24   5  85  24  24  24  75   3  24  24   3   0   0  24   0   3
T |  87   0  24   0   0  85  24  85   3  24  24  24   3  87  24  24   5  96   0  24   0   3

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updated Sat Dec 14 15:47:43 2024