6o6p_B : 3D-footprint complex

structure name	STRUCTURE OF THE REGULATOR FASR FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH DNA (TetR family transcriptional regulator)
reference	Trajtenberg et al. 'Nat 11 3703 2020
source	Mycobacterium tuberculosis
experiment	X-ray (resolution=3.85, R-factor=0.292)
structural superfamily	Tetracyclin repressor-like, C-terminal domain;Homeodomain-like;
sequence family	Bacterial regulatory proteins, tetR family;
multimeric complexes	6o6p_AB
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6o6p_B interface=35,36,37,40, derrgqllvvasdvfvdrgyhaagmdeiadragvSKPvlYqhfssklelylavlhrhvenlvsgvhqalstttdnrqrlhvavqaffdfiehdsqgyrlifendfvtepevaaqvrvatescidavfalisadsgldphrarmiavglvgmsvdcarywldadkpisksdavegtvqfawgglshvp
interface signature	SKPY

Estimated binding specificities ?

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# IC=3.101 IC/col=0.775 n_of_columns=4

specificity:

A |   0   0  54  13
C |   0   0  13  54
G |  96   0  13  16
T |   0  96  16  13

scan!

Dendrogram of similar interfaces ?

matrix format

  
  ----SGKGPT--YG--   L                           +6o6p_B    
                                      +----------2 
  TA--AT----LCFGHA                    !          +4i6z_B    
                              +-------5 
  TG--SAKG--NTYTYT   L        !       !        +--1jt0_C    
                              !       +--------3 
  TA--STECAGATYTRG   L        !                !  +4gck_A    
                         +----6                +--1 
  TA----ECAGATYCRG   L   !    !                   +5k58_E    
                         !    ! 
  LG----KG--STYTHT   L --7    !                +--4l62_M    
                         !    +----------------4 
  ------KG----YT--       !                     +--6wpa_A    
                         ! 
  --RC----PTTC--WC   L   +------------------------1qpi_A

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updated Tue Dec 19 13:54:54 2023