interface graph thumbnail
legend  pdf

structure nameSTRUCTURE OF THE REGULATOR FASR FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH DNA
(TetR family transcriptional regulator)
referenceTrajtenberg et al. 'Nat 11 3703 2020
sourceMycobacterium tuberculosis
experimentX-ray (resolution=3.85, R-factor=0.292)
structural superfamilyTetracyclin repressor-like, C-terminal domain;Homeodomain-like;
sequence familyBacterial regulatory proteins, tetR family;
multimeric complexes6o6p_AB
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSKPY

Estimated binding specificities ?

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# IC=3.101 IC/col=0.775 n_of_columns=4 specificity:   
A |   0   0  54  13
C |   0   0  16  54
G |  96   0  13  13
T |   0  96  13  16
scan!

Dendrogram of similar interfaces ?

matrix format
  
  ----SGKGPT--YG--   L                           +6o6p_B    
                                      +----------2 
  TA--AT----LCFGHA                    !          +4i6z_B    
                              +-------5 
  TG--SAKG--NTYTYT   L        !       !        +--1jt0_C    
                              !       +--------3 
  TA--STECAGATYTRG   L        !                !  +4gck_A    
                         +----6                +--1 
  TA----ECAGATYCRG   L   !    !                   +5k58_E    
                         !    ! 
  LG----KG--STYTHT   L --7    !                +--4l62_M    
                         !    +----------------4 
  ------KG----YT--       !                     +--6wpa_A    
                         ! 
  --RC----PTTC--WC   L   +------------------------1qpi_A    
                       

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updated Fri Sep 13 22:48:08 2024