interface graph thumbnail
legend  pdf

structure nameSTRUCTURE OF HIV CLEAVED SYNAPTIC COMPLEX (CSC) INTASOME BOUND WITH MAGNESIUM AND INSTI XZ446 (COMPOUND 4F)
referenceJozwik et al. Science 367 810 2020
experimentX-ray (resolution=2.80, R-factor=0.535)
structural superfamilyRibonuclease H-like;N-terminal Zn binding domain of HIV integrase;DNA-binding domain of retroviral integrase;
sequence familyIntegrase core domain; Integrase Zinc binding domain; Integrase DNA binding domain;
multimeric complexes6put_ACD 6puw_AC 6puy_ABC 6puz_ABC 6v3k_ABC
reference complex6puy_D
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence

No structural evidence for specific binding to DNA (<4 informative columns)


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updated Fri Sep 13 01:33:40 2024