interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF THE RBPJ-NOTCH1-NRARP TERNARY COMPLEX BOUND TO DNA
(RECOMBINING BINDING PROTEIN SUPPRESSOR OF HAIRLESS)
referenceSeegar et al. Sci.Signal. 12 ? 2019
sourceHOMO SAPIENS
experimentX-ray (resolution=3.75, R-factor=0.270)
structural superfamilyp53-like transcription factors;DNA-binding protein LAG-1 CSL;E set domains;
sequence familyBetatrefoil; LAG1, DNA binding; IPT/TIG domain;
multimeric complexes3nbn_AD
reference complex3iag_C
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureYERSKSQ

Estimated binding specificities ?

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# IC=6.879 IC/col=0.860 n_of_columns=8 specificity:   
A |   3   3   5  16   9   0  96  92
C |   4   3   3  18   3   0   0   1
G |   3  86  16  49  66  96   0   0
T |  86   4  72  13  18   0   0   3
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updated Sat Aug 2 13:38:03 2025