interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF THE RBPJ-NOTCH1-NRARP TERNARY COMPLEX BOUND TO DNA
(RECOMBINING BINDING PROTEIN SUPPRESSOR OF HAIRLESS)
referenceSeegar et al. Sci.Signal. 12 ? 2019
sourceHOMO SAPIENS
experimentX-ray (resolution=3.75, R-factor=0.270)
structural superfamilyp53-like transcription factors;DNA-binding protein LAG-1 CSL;E set domains;
sequence familyBetatrefoil; LAG1, DNA binding; IPT/TIG domain;
multimeric complexes3nbn_AD
reference complex3iag_C
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureYERSKSQ

Estimated binding specificities ?

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# IC=6.886 IC/col=0.861 n_of_columns=8 specificity:   
A |   3   4   9  16   3   0  96  92
C |   3   3   3  16   6   0   0   0
G |   3  86  17  48  70  96   0   0
T |  87   3  67  16  17   0   0   4
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updated Fri Jan 9 09:25:24 2026