interface graph thumbnail
legend  pdf

structure nameKOD DNA POL IN A CLOSED TERNARY COMPLEX WITH 7-DEAZA-7-(2-(2- HYDROXYETHOXY)-N-(PROP-2-YN-1-YL)ACETAMIDE)-2-DATP
referenceDiederichs et al. Angew.Chem.Int.Ed.Engl. 58 5457 2019
experimentX-ray (resolution=2.00, R-factor=0.204)
structural superfamilyDNA/RNA polymerases;Ribonuclease H-like;
sequence familyDNA polymerase family B; DNA polymerase family B, exonuclease do;
redundant complexes5omf 5vu9 4k8z 6wya 5vu6 5vu8 5vu7 6wyb
reference complex7om3_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureYYKR

Estimated binding specificities ?

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# IC=2.340 IC/col=0.585 n_of_columns=4 specificity:   
A |   7   7   7  73
C |   7  75  73   7
G |  75   7   7   9
T |   7   7   9   7
scan!

Dendrogram of similar interfaces ?

matrix format

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updated Fri Sep 13 01:37:59 2024