6qtk_ABCD : 3D-footprint complex

structure name	2.31A STRUCTURE OF GEPOTIDACIN WITH S.AUREUS DNA GYRASE AND DOUBLY NICKED DNA
reference	'Acs 5 570 2019 X-RAY DIFFRACTION
source	STAPHYLOCOCCUS AUREUS / STAPHYLOCOCCUS AUREUS (STRAIN N315) / STAPHYLOCOCCUS AUREUS (STRAIN N315) / STAPHYLOCOCCUS AUREUS (STRAIN N315) / STAPHYLOCOCCUS AUREUS (STRAIN N315)
experiment	X-ray (resolution=2.31, R-factor=?)
structural superfamily	Type II DNA topoisomerase;
reference complex	5iwi_C 5iwi_D
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6qtk_A interface=18,26,78,168, rinernitsemresfldYamsvivaRalpdvrdglkpvhrrilyglneqgmtpdksykksarivgdvmgkyhphgdsSiyeamvrmaqdfsyryplvdgqgnfgsmdgdgaaamrftearmtkitlellrdinkdtidfidnydgnerepsvlparfpnllangasgIavgmatnipphnltelingvlslsknpdisiaelmediegpdfptaglilgksgirrayetgrgsiqmrsravieergggrqrivvteipfqvnkarmiekiaelvrdkkidgitdlrdetslrtgvrvvidvrkdanasvilnnlykqtplqtsfgvnmialvngrpklinlkealvhylehqktvvrrrtqynlrkakdrahileglrialdhideiistiresdtdkvameslqqrfklsekqaqaildmrlrrltglerdkieaeynellnyiseletiladeevllqlvrdelteirdrfgddrrteiqlg > 6qtk_B interface=44,46, pgkladcsskspeeceiflvegdsaggstksgrdsrtqailplRgKilnvekarldrilnnneirqmitafgtgiggdfdlakaryhkivimtdadvdgahirtllltffyrfmrplieagyvyiaqpptgykglgemnadqlwettmnpehrallqvkledaieadqtfemlmgdvvenrrqfiednavya > 6qtk_C interface=17,76,77,167, inernitsemresfldYamsvivaralpdvrdglkpvhrrilyglneqgmtpdksykksarivgdvmgkyhphgdSSiyeamvrmaqdfsyryplvdgqgnfgsmdgdgaaamrftearmtkitlellrdinkdtidfidnydgnerepsvlparfpnllangasgIavgmatnipphnltelingvlslsknpdisiaelmediegpdfptaglilgksgirrayetgrgsiqmrsravieergggrqrivvteipfqvnkarmiekiaelvrdkkidgitdlrdetslrtgvrvvidvrkdanasvilnnlykqtplqtsfgvnmialvngrpklinlkealvhylehqktvvrrrtqynlrkakdrahileglrialdhideiistiresdtdkvameslqqrfklsekqaqaildmrlrrltglerdkieaeynellnyiseletiladeevllqlvrdelteirdrfgddrrteiql > 6qtk_D interface=44,46, pgkladcsskspeeceiflvegdsaggstksgrdsrtqailplRgKilnvekarldrilnnneirqmitafgtgiggdfdlakaryhkivimtdadvdgahirtllltffyrfmrplieagyvyiaqpptgykglgemnadqlwettmnpehrallqvkledaieadqtfemlmgdvvenrrqfiednavya
interface signature	YRSI/RK/YSSI/RK

Estimated binding specificities ?

readout + contact

# IC=8.729 IC/col=0.623 n_of_columns=14

specificity:

A |   0   0   1  28   7  24   1  24   5  24   5  24   0   0
C |  96   0   1   7  19  24   3  24  48  24  52  24  96   0
G |   0  96   0  55  57  24   8  24   9  24   5  24   0  96
T |   0   0  94   6  13  24  84  24  34  24  34  24   0   0

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updated Thu Jun 25 22:06:14 2026