6qtk_ABCD : 3D-footprint complex

structure name	2.31A STRUCTURE OF GEPOTIDACIN WITH S.AUREUS DNA GYRASE AND DOUBLY NICKED DNA
reference	'Acs 5 570 2019 X-RAY DIFFRACTION
source	STAPHYLOCOCCUS AUREUS / STAPHYLOCOCCUS AUREUS (STRAIN N315) / STAPHYLOCOCCUS AUREUS (STRAIN N315) / STAPHYLOCOCCUS AUREUS (STRAIN N315) / STAPHYLOCOCCUS AUREUS (STRAIN N315)
experiment	X-ray (resolution=2.31, R-factor=?)
structural superfamily	Type II DNA topoisomerase;
reference complex	5iwi_C 5iwi_D
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6qtk_A interface=18,26,78,168, rinernitsemresfldYamsvivaRalpdvrdglkpvhrrilyglneqgmtpdksykksarivgdvmgkyhphgdsSiyeamvrmaqdfsyryplvdgqgnfgsmdgdgaaamrftearmtkitlellrdinkdtidfidnydgnerepsvlparfpnllangasgIavgmatnipphnltelingvlslsknpdisiaelmediegpdfptaglilgksgirrayetgrgsiqmrsravieergggrqrivvteipfqvnkarmiekiaelvrdkkidgitdlrdetslrtgvrvvidvrkdanasvilnnlykqtplqtsfgvnmialvngrpklinlkealvhylehqktvvrrrtqynlrkakdrahileglrialdhideiistiresdtdkvameslqqrfklsekqaqaildmrlrrltglerdkieaeynellnyiseletiladeevllqlvrdelteirdrfgddrrteiqlg > 6qtk_B interface=44,46, pgkladcsskspeeceiflvegdsaggstksgrdsrtqailplRgKilnvekarldrilnnneirqmitafgtgiggdfdlakaryhkivimtdadvdgahirtllltffyrfmrplieagyvyiaqpptgykglgemnadqlwettmnpehrallqvkledaieadqtfemlmgdvvenrrqfiednavya > 6qtk_C interface=17,76,77,167, inernitsemresfldYamsvivaralpdvrdglkpvhrrilyglneqgmtpdksykksarivgdvmgkyhphgdSSiyeamvrmaqdfsyryplvdgqgnfgsmdgdgaaamrftearmtkitlellrdinkdtidfidnydgnerepsvlparfpnllangasgIavgmatnipphnltelingvlslsknpdisiaelmediegpdfptaglilgksgirrayetgrgsiqmrsravieergggrqrivvteipfqvnkarmiekiaelvrdkkidgitdlrdetslrtgvrvvidvrkdanasvilnnlykqtplqtsfgvnmialvngrpklinlkealvhylehqktvvrrrtqynlrkakdrahileglrialdhideiistiresdtdkvameslqqrfklsekqaqaildmrlrrltglerdkieaeynellnyiseletiladeevllqlvrdelteirdrfgddrrteiql > 6qtk_D interface=44,46, pgkladcsskspeeceiflvegdsaggstksgrdsrtqailplRgKilnvekarldrilnnneirqmitafgtgiggdfdlakaryhkivimtdadvdgahirtllltffyrfmrplieagyvyiaqpptgykglgemnadqlwettmnpehrallqvkledaieadqtfemlmgdvvenrrqfiednavya
interface signature	YRSI/RK/YSSI/RK

Estimated binding specificities ?

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# IC=11.195 IC/col=0.800 n_of_columns=14

specificity:

A |   0   0  24  26   0  31   1  94  24   3   1  94   0   0
C |  96   0  24   4  11   1  39   1  24  69  84   0  96   0
G |   0  96  24  55  61  63   7   1  24  21   0   0   0  96
T |   0   0  24  11  24   1  49   0  24   3  11   2   0   0

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updated Tue Sep 10 19:11:45 2024