6qtp_ABCD : 3D-footprint complex

structure name	2.37A STRUCTURE OF GEPOTIDACIN WITH S.AUREUS DNA GYRASE AND UNCLEAVED DNA
reference	'Acs 5 570 2019 Escherichia coli
source	STAPHYLOCOCCUS AUREUS
experiment	X-ray (resolution=2.37, R-factor=?)
structural superfamily	Type II DNA topoisomerase;
reference complex	5iwi_C 5iwi_D
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6qtp_A interface=74,75,165, ernitsemresfldyamsvivaralpdvrdglkpvhrrilyglneqgmtpdksykksarivgdvmgkyhphgdSSiyeamvrmaqdfsyryplvdgqgnfgsmdgdgaaamrytearmtkitlellrdinkdtidfidnydgnerepsvlparfpnllangasgIavgmatnipphnltelingvlslsknpdisiaelmediegpdfptaglilgksgirrayetgrgsiqmrsravierqrivvteipfqvnkarmiekiaelvrdkkidgitdlrdetslrtgvrvvidvrkasvilnnlykqtplqtsfgvnmialvngrpklinlkealvhylehqktvvrrrtqynlrkakdrahileglrialdhideiistiresdtdkvameslqqrfklsekqaqaildmrlrrltglerdkieaeynellnyiseletiladeevllqlvrdelteirdrfgddrrteiqlg > 6qtp_B interface=43,45, gkladcsskspeeceiflvegdsaggstksgrdsrtqailplRgKilnvekarldrilnnneirqmitafgtgiggdfdlakaryhkivimtdadvdgahirtllltffyrfmrplieagyvyiaqppykglgemnadqlwettmnpehrallqvkledaieadqtfemlmgdvvenrrqfiednavya > 6qtp_C interface=16,76,79,166, nernitsemresfldYamsvivaralpdvrdglkpvhrrilyglneqgmtpdksykksarivgdvmgkyhphgdsSiyEamvrmaqdfsyryplvdgqgnfgsmdgdgaaamrytearmtkitlellrdinkdtidfidnydgnerepsvlparfpnllangasgIavgmatnipphnltelingvlslsknpdisiaelmediegpdfptaglilgksgirrayetgrgsiqmrsravieergggrqrivvteipfqvnkarmiekiaelvrdkkidgitdlrdetslrtgvrvvidvrkdanasvilnnlykqtplqtsfgvnmialvngrpklinlkealvhylehqktvvrrrtqynlrkakdrahileglrialdhideiistiresdtdkvameslqqrfklsekqaqaildmrlrrltglerdkieaeynellnyiseletiladeevllqlvrdelteirdrfgddrrteiql > 6qtp_D interface=44, kladcsskspeeceiflvegdsaggstksgrdsrtqailplrgKilnvekarldrilnnneirqmitafgtgiggdfdlakaryhkivimtdadvdgahirtllltffyrfmrplieagyvyiaqpptgykglgemnadqlwettmnpehrallqvkledaieadqtfemlmgdvvenrrqfiednavya
interface signature	SSI/RK/YSEI/K

Estimated binding specificities ?

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# IC=6.707 IC/col=0.479 n_of_columns=14

specificity:

A |   0   0   4  50   5  24  24  24  24  24  10  24   0   0
C |  96   0  35  16  79  24  24  24  24  24  16  24  96   0
G |   0  96  12  12   4  24  24  24  24  24  16  24   0  96
T |   0   0  45  18   8  24  24  24  24  24  54  24   0   0

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updated Tue Sep 10 19:12:45 2024