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structure nameCRYSTAL STRUCTURE OF THE DOUBLE HOMEODOMAIN OF DUX4 IN COMPLEX WITH A DNA APTAMER CONTAINING BULGE AND LOOP
(Double homeobox protein 4)
referenceAihara et al. 'Faseb 34 4573 2020
sourceHomo sapiens
experimentX-ray (resolution=3.21, R-factor=0.253)
structural superfamilyHomeodomain-like;
sequence familyHomeobox domain;
reference complex5zfz_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRRIQNSRRIQNR

Estimated binding specificities ?

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# IC=11.222 IC/col=0.935 n_of_columns=12 specificity:   
A |   0   0  78  12   0  78   0  66  24   0   0  84
C |  96   6   6   0   0   6   0  12  24   0  96   6
G |   0   0   6   6   0   6   0  12  24   0   0   0
T |   0  90   6  78  96   6  96   6  24  96   0   6
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updated Fri Sep 13 02:19:02 2024