interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF THE DOUBLE HOMEODOMAIN OF DUX4 IN COMPLEX WITH A DNA APTAMER CONTAINING BULGE AND LOOP
(Double homeobox protein 4)
referenceAihara et al. 'Faseb 34 4573 2020
sourceHomo sapiens
experimentX-ray (resolution=3.21, R-factor=0.253)
structural superfamilyHomeodomain-like;
sequence familyHomeobox domain;
multimeric complexes5z2t_CD 6dfy_CD
reference complex6a8r_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRRIQNSRRIQNR

Estimated binding specificities ?

readout + contactlogo
# IC=11.076 IC/col=0.923 n_of_columns=12 specificity:   
A |   0   1  79  13   0  79   0  67  24   0   0  84
C |  96   5   5   5   0   5   0  11  24   0  96   5
G |   0   0   5   5   0   7   0  13  24   0   0   2
T |   0  90   7  73  96   5  96   5  24  96   0   5
scan!

home
updated Fri Jan 9 10:21:07 2026