6u82_A : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF THE DOUBLE HOMEODOMAIN OF DUX4 IN COMPLEX WITH A DNA APTAMER CONTAINING BULGE AND LOOP (Double homeobox protein 4)
reference	Aihara et al. 'Faseb 34 4573 2020
source	Homo sapiens
experiment	X-ray (resolution=3.21, R-factor=0.253)
structural superfamily	Homeodomain-like;
sequence family	Homeobox domain;
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6u82_A interface=2,5,47,50,51,54,77,80,122,125,126,130, gRrrRlvwtpsqsealracfernpypgiatrerlaqaigipeprvqIwfQNerSrqlrqhrresrpwpgrrgppegRrkRtavtgsqtalllrafekdrfpgiaareelaretglpesriqIwfQNrraRhp
interface signature	RRIQNSRRIQNR

Estimated binding specificities ?

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# IC=11.222 IC/col=0.935 n_of_columns=12

specificity:

A |   0   0  78  12   0  78   0  66  24   0   0  84
C |  96   6   6   0   0   6   0  12  24   0  96   6
G |   0   0   6   6   0   6   0  12  24   0   0   0
T |   0  90   6  78  96   6  96   6  24  96   0   6

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updated Tue Dec 17 07:16:31 2024