interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF ACECAS9 BOUND WITH GUIDE RNA AND DNA WITH 5'- NNNTC-3' PAM
referenceDas et al. 'Nat 11 6346 2020
experimentX-ray (resolution=3.61, R-factor=0.244)
reference complex6wbr_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRERR

Estimated binding specificities ?

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# IC=3.037 IC/col=0.506 n_of_columns=6 specificity:   
A |  70   3  57  24  24   0
C |   8   3  13  24  24   0
G |   8  87  13  24  24   0
T |  10   3  13  24  24  96
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updated Fri Jan 9 11:02:09 2026