6wc5_CDN : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF A TERNARY MEF2B/NKX2-5/MYOCARDIN ENHANCER DNA COMPLEX
reference	Chen et al. J.Mol.Biol. 432 5499 2020
source	HOMO SAPIENS
experiment	X-ray (resolution=2.90, R-factor=?)
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6wc5_C interface=2,14,22, gRkkiqisrildqRnrqvtftKrkfglmkkayelsvlcdceialiifnsanrlfqyastdmdrvllkyteysephesrtntdiletlkrr > 6wc5_D interface=2,18,22, gRkkiqisrildqrnrqVtftKrkfglmkkayelsvlcdceialiifnsanrlfqyastdmdrvllkyteysephesrtntdiletlkrr > 6wc5_N interface=3,44,45,48,49,52, kpRvlfsqaqvyelerrfkqqrylsaperdqlasvlkltstqvKIwfQNrrYksk
interface signature	RRK/RVK/RKIQNY

Estimated binding specificities ?

readout + contact

# IC=9.722 IC/col=0.648 n_of_columns=15

specificity:

A |   0   5   0   0   0   0   5  24  24  24  24  24   5  85   0
C |   6  74   0   5   5  96  58  24  24  24  24  24   5   0   0
G |   5  10   0   1   1   0  12  24  24  24  24  24   6  10  96
T |  85   7  96  90  90   0  21  24  24  24  24  24  80   1   0

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updated Sat Dec 14 22:42:44 2024