interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF A TERNARY MEF2B/NKX2-5/MYOCARDIN ENHANCER DNA COMPLEX
referenceChen et al. J.Mol.Biol. 432 5499 2020
sourceHOMO SAPIENS
experimentX-ray (resolution=2.90, R-factor=?)
structural superfamilySRF-like;
reference complex1n6j_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRRK/RVK/RKIQNY

Estimated binding specificities ?

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# IC=9.879 IC/col=0.659 n_of_columns=15 specificity:   
A |   0   5   0   0   0   0   0  24  24  24  24  24   5  86   0
C |  10  74   0   0  10  96  53  24  24  24  24  24  12   0   0
G |   5  10   0   0   0   0   6  24  24  24  24  24   5  10  96
T |  81   7  96  96  86   0  37  24  24  24  24  24  74   0   0
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updated Tue Jan 6 15:53:28 2026