interface graph thumbnail
legend  pdf

structure nameCSL (RBPJ) BOUND TO NOTCH3 RAM AND DNA
(RECOMBINING BINDING PROTEIN SUPPRESSOR OF HAIRLESS)
referenceKovall et al. J.Biol.Chem. 296 100593 2021
sourceMUS MUSCULUS
experimentX-ray (resolution=2.41, R-factor=0.201)
structural superfamilyp53-like transcription factors;DNA-binding protein LAG-1 CSL;E set domains;
sequence familyBetatrefoil; LAG1, DNA binding; IPT/TIG domain;
multimeric complexes3nbn_AD
reference complex3iag_C
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureYERSKKSQ

Estimated binding specificities ?

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# IC=7.099 IC/col=1.014 n_of_columns=7 specificity:   
A |   0   0   0   0  96  16  13
C |   0  96  96  96   0  54  13
G |   0   0   0   0   0  13  54
T |  96   0   0   0   0  13  16
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updated Sat Aug 2 15:09:20 2025