6x6d_AB : 3D-footprint complex

structure name	GLUCOCORTICOID RECEPTOR DNA BINDING DOMAIN IN COMPLEX WITH UNMODIFIED PRECURSOR FOR A MODERN RECOGNITION ELEMENT (PRE-GBS)
reference	Ortlund et al. 'Nucleic 49 8923 2021
source	Homo sapiens
experiment	X-ray (resolution=2.48, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
reference complex	3g9m_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6x6d_A interface=26,27,31, ppklclvcsdeasgchygvltcgscKVffkRavegqhnylcagrndciidkirrkncpacryrkclqagmnlea > 6x6d_B interface=25,26,30, pklclvcsdeasgchygvltcgscKVffkRavegqhnylcagrndciidkirrkncpacryrkclqagmnlea
interface signature	KVR/KVR

Estimated binding specificities ?

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# IC=7.700 IC/col=0.592 n_of_columns=13

specificity:

A |   0  24  59   0   7  24  24  24   7   0  14  24   0
C |   0  24  14  96   9  24  24  24  88   0  14  24  96
G |  96  24  14   0  73  24  24  24   0  96   2  24   0
T |   0  24   9   0   7  24  24  24   1   0  66  24   0

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updated Tue Jan 6 17:30:50 2026