6x6d_AB : 3D-footprint complex

structure name	GLUCOCORTICOID RECEPTOR DNA BINDING DOMAIN IN COMPLEX WITH UNMODIFIED PRECURSOR FOR A MODERN RECOGNITION ELEMENT (PRE-GBS)
reference	Ortlund et al. 'Nucleic 49 8923 2021
source	Homo sapiens
experiment	X-ray (resolution=2.48, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
reference complex	3g9m_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6x6d_A interface=26,27,31, ppklclvcsdeasgchygvltcgscKVffkRavegqhnylcagrndciidkirrkncpacryrkclqagmnlea > 6x6d_B interface=25,26,30, pklclvcsdeasgchygvltcgscKVffkRavegqhnylcagrndciidkirrkncpacryrkclqagmnlea
interface signature	KVR/KVR

Estimated binding specificities ?

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# IC=7.671 IC/col=0.590 n_of_columns=13

specificity:

A |   0  24  61   0   6  24  24  24   6   0   6  24   0
C |   0  24  13  96   6  24  24  24  75   0   6  24  96
G |  96  24   6   0  84  24  24  24   6  96  16  24   0
T |   0  24  16   0   0  24  24  24   9   0  68  24   0

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updated Sun Dec 15 00:08:41 2024