6x6e_AB : 3D-footprint complex

structure name	GLUCOCORTICOID RECEPTOR DNA BINDING DOMAIN IN COMPLEX WITH METHYLATED PRECURSOR FOR A MODERN RECOGNITION ELEMENT (METHYLATED PRE-GBS)
reference	Ortlund et al. 'Nucleic 49 8923 2021
source	Homo sapiens
experiment	X-ray (resolution=2.00, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
reference complex	3g9m_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6x6e_A interface=24,25,29, klclvcsdeasgchygvltcgscKVffkRavegqhnylcagrndciidkirrkncpacryrkclqagmnlear > 6x6e_B interface=24,25,29, klclvcsdeasgchygvltcgscKVffkRavegqhnylcagrndciidkirrkncpacryrkclqagmnle
interface signature	KVR/KVR

Estimated binding specificities ?

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# IC=5.564 IC/col=0.428 n_of_columns=13

specificity:

A |   0  24  36   0  24  24  24  24  24   0  12  24   0
C |   0  24  24  96  24  24  24  24  24   0  24  24  96
G |  96  24  24   0  24  24  24  24  24  96  12  24   0
T |   0  24  12   0  24  24  24  24  24   0  48  24   0

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updated Sun Dec 15 00:08:51 2024