6xgw_AB : 3D-footprint complex

structure name	ISCTH4 TRANSPOSASE, PRE-REACTION COMPLEX, PRC
reference	Kosek et al. 'Embo 40 e105666 2021
experiment	X-ray (resolution=3.50, R-factor=?)
structural superfamily	Ribonuclease H-like;
reference complex	6xg8_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6xgw_A interface=54,64,66,69,86,88,100,102,121,122,137,138,139,142,357,358,360, iitpekkelirnliseynitsakdlqealkdllgdtiqnmleaeldehlgyekYesteeaksnYrNgyTsktlkssvgqveidipRdRnaefepkivprYkRdiseienkiiamyargmsTReineqiqeiygfevSAEmvSkitdkilpeieewqkrplgevypivfidaihfsvkndgivgkkavyivlaidiegqkdvigiyvgenesskfwlsvlndlknrgvkdililcadalsgikdainaafpnteyqrcivhqirntlkyvsdkdrkefardlkriytapnekagydqmlevsekwekkypaamkswksnwdvicpffkyseelrkimyttntieslnssyrrinksrTVfPgdqsllksiylatvkitskwtmryknwglilgqlqimfegr > 6xgw_B interface=234,237,238, kriitpekkelirnliseynitsakdlqealkdllgdtiqnmleaeldehlgprykrdiseienkiiamyargmstreineqiqeiygfevsaemvskitdkilpeieewqkrplgevypivfidaihfsvkndgivgkkavyivlaidiegqkdvigiyvgenesskfwlsvlndlknrgvkdililcadalsgikdainaafpnteyqrcivhqirntlkyvsdkdrkefaRdlKRiytapnekagydqmlevsekwekkypaamkswksnwdvicpffkyseelrkimyttntieslnssyrrinksrtvfpgdqsllksiylatvkitskwtmryknwglilgqlqimfegr
interface signature	YYNTRRYRTRSAESTVP/RKR

Estimated binding specificities ?

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# IC=21.331 IC/col=0.736 n_of_columns=29

specificity:

A |   0  10   8  24  24  24  24   7   0   0   0  96  96  24  24  24  24   1  12   9   0  24   0   0   0  72  96  96   1
C |   0  11   9  24  24  24  24   7   0   0   0   0   0  24  24  24  24   4   5  10   0  24   0   0   0   5   0   0  90
G |   0   9  74  24  24  24  24  74   0  96   0   0   0  24  24  24  24   1   5   9   0  24   0  96   0  12   0   0   1
T |  96  66   5  24  24  24  24   8  96   0  96   0   0  24  24  24  24  90  74  68  96  24  96   0  96   7   0   0   4

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updated Fri Jun 26 04:23:43 2026