interface graph thumbnail
legend  pdf

structure nameISCTH4 TRANSPOSASE, PRE-REACTION COMPLEX, PRC
referenceKosek et al. 'Embo 40 e105666 2021
experimentX-ray (resolution=3.50, R-factor=?)
structural superfamilyRibonuclease H-like;
reference complex6xg8_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureYYNTRRYRTRSAESTVP/RKR

Estimated binding specificities ?

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# IC=21.693 IC/col=0.748 n_of_columns=29 specificity:   
A |   0   7   5  24  24  24  24   9   0   0   0  96  96  24  24  24  24   1   9   9   0  24   0   0   0  81  96  96   1
C |   0  11  12  24  24  24  24  10   0   0   0   0   0  24  24  24  24   4   8   7   0  24   0   0   0   5   0   0  93
G |   0  12  74  24  24  24  24  72   0  96   0   0   0  24  24  24  24   1   5   9   0  24   0  96   0   7   0   0   1
T |  96  66   5  24  24  24  24   5  96   0  96   0   0  24  24  24  24  90  74  71  96  24  96   0  96   3   0   0   1
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updated Tue Jan 6 17:49:59 2026