6xwh_CD : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF THE HUMAN RXR DNA-BINDING DOMAIN HOMODIMER BOUND TO THE HUMAN HOXB13 DR0 RESPONSE ELEMENT
reference	Poussin-Courmontagne et al. 'Nucleic 48 9969 2020
source	Homo sapiens
experiment	X-ray (resolution=2.10, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
reference complex	6fbq_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6xwh_C interface=23,26,30,31,79, tkhicaicgdrssgkhygvyscEgcKgffKRtvrkdltytcrdnkdclidkrqrnrcqycryqkclamgmkreavqeeRq > 6xwh_D interface=22,25,29,30, khicaicgdrssgkhygvyscEgcKgffKRtvrkdltytcrdnkdclidkrqrnrcqycryqkclamgmkreavqeer
interface signature	EKKRR/EKKR

Estimated binding specificities ?

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# IC=8.940 IC/col=0.813 n_of_columns=11

specificity:

A |   9   0  14   0  24  24   7   0  66   0   0
C |   7   0   7  96  24  24   0   0   9  96  96
G |   7  96  68   0  24  24   8  96  14   0   0
T |  73   0   7   0  24  24  81   0   7   0   0

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updated Wed Sep 11 01:05:41 2024