6xwh_CD : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF THE HUMAN RXR DNA-BINDING DOMAIN HOMODIMER BOUND TO THE HUMAN HOXB13 DR0 RESPONSE ELEMENT
reference	Poussin-Courmontagne et al. 'Nucleic 48 9969 2020
source	Homo sapiens
experiment	X-ray (resolution=2.10, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
reference complex	6fbq_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6xwh_C interface=23,26,30,31,79, tkhicaicgdrssgkhygvyscEgcKgffKRtvrkdltytcrdnkdclidkrqrnrcqycryqkclamgmkreavqeeRq > 6xwh_D interface=22,25,29,30, khicaicgdrssgkhygvyscEgcKgffKRtvrkdltytcrdnkdclidkrqrnrcqycryqkclamgmkreavqeer
interface signature	EKKRR/EKKR

Estimated binding specificities ?

readout + contact

# IC=9.020 IC/col=0.820 n_of_columns=11

specificity:

A |   9   0   7   0  24  24   9   0  81   0   0
C |   7   0   7  96  24  24   7   0   7  96  96
G |   7  96  66   0  24  24   7  96   7   0   0
T |  73   0  16   0  24  24  73   0   1   0   0

scan!

home
updated Thu Jul 31 06:46:14 2025