6yl2_AB : 3D-footprint complex

structure name	STRUCTURAL AND DNA BINDING STUDIES OF THE TRANSCRIPTIONAL REPRESSOR RV2506 (BKAR) FROM MYCOBACTERIUM TUBERCULOSIS SUPPORTS A ROLE IN L- LEUCINE CATABOLISM
reference	Pritchard et al. 'To ? ? ?
source	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) / Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) / Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) / Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
experiment	X-ray (resolution=3.15, R-factor=?)
structural superfamily	Homeodomain-like;Tetracyclin repressor-like, C-terminal domain;
reference complex	6yl2_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6yl2_A interface=37,40,41, sdrrfqllaaaerlfaergflavrledigaaagvsgPaiYRhfpnkesllvellvgvsarllagardvttrsanlaaaldgliefhldfalgeadliriqdrdlahlpavaerqvrkaqrqyvevwvgvlrelnpglaeadarlmahavfgllnstphsmkaadskpartvraravlramtvaalsaadrcl > 6yl2_B interface=25,37,38,40,41, sdrrfqllaaaerlfaergflavrLedigaaagvsgPAiYRhfpnkesllvellvgvsarllagardvttrsanlaaaldgliefhldfalgeadliriqdrdlahlpavaerqvrkaqrqyvevwvgvlrelnpglaeadarlmahavfgllnstphsmkaadskpartvraravlramtvaalsaadrcl
interface signature	PYR/LPAYR

Estimated binding specificities ?

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# IC=10.630 IC/col=0.591 n_of_columns=18

specificity:

A |   0   0  24  11  67  96  24  24  24  24  24  24  11   0  96  24   0   0
C |  96   0  24   9   9   0  24  24  24  24  24  24   9   0   0  24  96  96
G |   0  96  24   9   9   0  24  24  24  24  24  24   9   0   0  24   0   0
T |   0   0  24  67  11   0  24  24  24  24  24  24  67  96   0  24   0   0

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updated Sun Dec 15 01:12:40 2024