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structure nameCRYO-EM STRUCTURE OF THE ENTIRE HUMAN TOPOISOMERASE II ALPHA IN STATE 1
experimentNMR
structural superfamilyType II DNA topoisomerase;ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase;Ribosomal protein S5 domain 2-like;
sequence familyDNA gyrase/topoisomerase IV, subunit A; DNA gyrase B; Histidine kinase, DNA gyrase B, and H;
multimeric complexes6zy5_AB 6zy7_AB
reference complex6zy5_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKSMEIS

Estimated binding specificities ?

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# IC=2.689 IC/col=0.538 n_of_columns=5 specificity:   
A |   8  61  24   8   0
C |  69  17  24  72   0
G |  11  10  24   8  96
T |   8   8  24   8   0
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updated Mon Dec 18 19:35:17 2023