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structure nameCRYO-EM STRUCTURE OF THE ENTIRE HUMAN TOPOISOMERASE II ALPHA IN STATE 2
experimentNMR
structural superfamilyType II DNA topoisomerase;ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase;Ribosomal protein S5 domain 2-like;
sequence familyDNA gyrase/topoisomerase IV, subunit A; DNA gyrase B; Histidine kinase, DNA gyrase B, and H;
multimeric complexes6zy5_AB 6zy7_AB
reference complex6zy5_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRKSMI

Estimated binding specificities ?

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# IC=4.475 IC/col=0.895 n_of_columns=5 specificity:   
A |  13  96  13   0   0
C |  57   0  16  96   0
G |  13   0  13   0  96
T |  13   0  54   0   0
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updated Mon Dec 18 19:35:48 2023