7b24_ABCD : 3D-footprint complex

structure name	DTXR-LIKE IRON-DEPENDENT REGULATOR IDER (P39G VARIANT) COMPLEXED WITH COBALT AND ITS CONSENSUS DNA-BINDING SEQUENCE
reference	Marcos-Torres et al.
experiment	X-ray (resolution=2.05, R-factor=?)
structural superfamily	Iron-dependent repressor protein, dimerization domain;C-terminal domain of transcriptional repressors;"Winged helix" DNA-binding domain;
reference complex	7b24_C
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 7b24_A interface=36,39,41,42,46, ndlidttemylrtiydleeegvvplrariaerleqSggTvSQtvaRmerdglltvaedrhleltkagraraisvmrkhrlaerllvdvigleweqvhleacrwehvmseaverklvkllgnpttspygnpipgldelgvgds > 7b24_B interface=36,39,42,46, ndlidttemylrtiydleeegvvplrariaerleqSggTvsQtvaRmerdglltvaedrhleltkagraraisvmrkhrlaerllvdvigleweqvhleacrwehvmseaverklvkllgnpttspygnpipgldelgvepvdtdlrrvdevarsgggralvcriaehvqldpdlmselkkvgvvpgneidivavagvnkpiqvqgseggtqlqpgiahavmvrvk > 7b24_C interface=36,39,42,46, ndlidttemylrtiydleeegvvplrariaerleqSggTvsQtvaRmerdglltvaedrhleltkagraraisvmrkhrlaerllvdvigleweqvhleacrwehvmseaverklvkllgnpttspygnpipgldelgpvdtdlrrvdevarsgggralvcriaehvqldpdlmselkkvgvvpgneidivavagvnkpiqvqgseggtqlqpgiahavmvrvk > 7b24_D interface=36,39,41,42,46, ndlidttemylrtiydleeegvvplrariaerleqSggTvSQtvaRmerdglltvaedrhleltkagraraisvmrkhrlaerllvdvigleweqvhleacrwehvmseaverklvkllgnpttspygnpipgldelgvgds
interface signature	STSQR/STQR/STQR/STSQR

Estimated binding specificities ?

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# IC=6.028 IC/col=0.464 n_of_columns=13

specificity:

A |  12   0  24  24  24   8   7   8  24  24  24   0   6
C |   6   0  24  24  24   6  89  76  24  24  24  96  70
G |  70  96  24  24  24  76   0   6  24  24  24   0   8
T |   8   0  24  24  24   6   0   6  24  24  24   0  12

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updated Thu Jul 31 08:29:28 2025