7b25_ABCD : 3D-footprint complex

structure name	DTXR-LIKE IRON-DEPENDENT REGULATOR IDER (Q43A VARIANT) COMPLEXED WITH COBALT AND ITS CONSENSUS DNA-BINDING SEQUENCE
reference	Marcos-Torres et al.
experiment	X-ray (resolution=2.34, R-factor=?)
structural superfamily	Iron-dependent repressor protein, dimerization domain;C-terminal domain of transcriptional repressors;"Winged helix" DNA-binding domain;
reference complex	7b24_C
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 7b25_A interface=35,37,38,40,45, dlidttemylrtiydleeegvvplrariaerleqSgPTvSatvaRmerdglltvaedrhleltkagraraisvmrkhrlaerllvdvigleweqvhleacrwehvmseaverklvkllgnpttspygnpipgldelgv > 7b25_B interface=35,37,38,40,45,58, dlidttemylrtiydleeegvvplrariaerleqSgPTvSatvaRmerdglltvaedRhleltkagraraisvmrkhrlaerllvdvigleweqvhleacrwehvmseaverklvkllgnpttspygnpipgldelgvsvepvdtdlrrvdevarsgggralvcriaehvqldpdlmselkkvgvvpgneidivavagvnkpiqvqgseggtqlqpgiahavmvrvk > 7b25_C interface=35,37,38,40,45, dlidttemylrtiydleeegvvplrariaerleqSgPTvSatvaRmerdglltvaedrhleltkagraraisvmrkhrlaerllvdvigleweqvhleacrwehvmseaverklvkllgnpttspygnpipgldelgvsvepvdtdlrrvdevarsgggralvcriaehvqldpdlmselkkvgvvpgneidivavagvnkpiqvqgseggtqlqpgiahavmvrvk > 7b25_D interface=35,37,38,40,45, dlidttemylrtiydleeegvvplrariaerleqSgPTvSatvaRmerdglltvaedrhleltkagraraisvmrkhrlaerllvdvigleweqvhleacrwehvmseaverklvkllgnpttspygnpipgldelgv
interface signature	SPTSR/SPTSRR/SPTSR/SPTSR

Estimated binding specificities ?

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# IC=21.095 IC/col=1.110 n_of_columns=19

specificity:

A |   1   1  96   0   4   0  15  96   1   4   0   0  69  96   1   1   0  67  93
C |   4   4   0   0   1   0   7   0   1   1  96   0   7   0  90  94   0  15   1
G |   1   1   0  96  90   0   5   0  94  90   0   0   7   0   4   1   0   7   1
T |  90  90   0   0   1  96  69   0   0   1   0  96  13   0   1   0  96   7   1

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updated Thu Jul 31 08:30:10 2025