7fvs_AB : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF S. AUREUS GYRASE IN COMPLEX WITH 4-[[1-[(1- CHLORO-6,7-DIHYDRO-5H-CYCLOPENTA[C]PYRIDIN-6-YL)METHYL]AZETIDIN-3- YL]METHYLAMINO]-6-FLUOROCHROMEN-2-ONE
reference	'Acs 2023
experiment	X-ray (resolution=2.16, R-factor=?)
structural superfamily	Type II DNA topoisomerase;
reference complex	5iwi_C
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 7fvs_A interface=44,205,213,264,265,302,355, kladcsskspeeceiflvegdsaggstksgrdsrtqailplrgKilnvekarldrilnnneirqmitafgtgiggdfdlakaryhkivimtdadvdgahirtllltffyrfmrplieagyvyiaqpptgykglgemnadqlwettmnpehrallqvkledaieadqtfemlmgdvvenrrqfiednavynernitsemresfldYamsvivaRalpdvrdglkpvhrrilyglneqgmtpdksykksarivgdvmgkyhphgdSSiyeamvrmaqdfsyryplvdgqgnfgsmdgdgaaamRftearmtkitlellrdinkdtidfidnydgnerepsvlparfpnllangasgIavgmatnipphnltelingvlslsknpdisiaelmediegpdfptaglilgksgirrayetgrgsiqmrsravieergggrqrivvteipfqvnkarmiekiaelvrdkkidgitdlrdetslrtgvrvvidvrkdanasvilnnlykqtplqtsfgvnmialvngrpklinlkealvhylehqktvvrrrtqynlrkakdrahileglrialdhideiistiresdtdkvameslqqrfklsekqaqaildmrlrrltglerdkieaeynellnyiseletiladeevllqlvrdelteirdrfgddrrteiql > 7fvs_B interface=42,44,205,265,268,302,355, kladcsskspeeceiflvegdsaggstksgrdsrtqailplRgKilnvekarldrilnnneirqmitafgtgiggdfdlakaryhkivimtdadvdgahirtllltffyrfmrplieagyvyiaqpptgykglgemnadqlwettmnpehrallqvkledaieadqtfemlmgdvvenrrqfiednavynernitsemresfldYamsvivaralpdvrdglkpvhrrilyglneqgmtpdksykksarivgdvmgkyhphgdsSiyEamvrmaqdfsyryplvdgqgnfgsmdgdgaaamRftearmtkitlellrdinkdtidfidnydgnerepsvlparfpnllangasgIavgmatnipphnltelingvlslsknpdisiaelmediegpdfptaglilgksgirrayetgrgsiqmrsravieergggrqrivvteipfqvnkarmiekiaelvrdkkidgitdlrdetslrtgvrvvidvrkdanasvilnnlykqtplqtsfgvnmialvngrpklinlkealvhylehqktvvrrrtqynlrkakdrahileglrialdhideiistiresdtdkvameslqqrfklsekqaqaildmrlrrltglerdkieaeynellnyiseletiladeevllqlvrdelteirdrfgddrrteiqlg
interface signature	KYRSSRI/RKYSERI

Estimated binding specificities ?

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# IC=7.951 IC/col=0.568 n_of_columns=14

specificity:

A |   0   0  24  24  14  24  24  24  11  16  16  96   0   0
C |  96   0  24  24  14  24  24  24  62  62   7   0  96   0
G |   0  96  24  24  55  24  24  24  12  11  11   0   0  96
T |   0   0  24  24  13  24  24  24  11   7  62   0   0   0

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updated Fri Jun 26 10:48:31 2026