7fvt_AB : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF S. AUREUS GYRASE IN COMPLEX WITH 6-[5-[2-[(4- CHLORO-2,3-DIHYDRO-1H-INDEN-2-YL)METHYLAMINO]ETHYL]-2-OXO-1,3- OXAZOLIDIN-3-YL]-4H-PYRIDO[3,2-B][1,4]OXAZIN-3-ONE
reference	'Acs 2023 X-RAY DIFFRACTION
experiment	X-ray (resolution=2.08, R-factor=?)
structural superfamily	Type II DNA topoisomerase;
reference complex	5npk_d
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 7fvt_A interface=42,44,205,264,265,302,355, kladcsskspeeceiflvegdsaggstksgrdsrtqailplRgKilnvekarldrilnnneirqmitafgtgiggdfdlakaryhkivimtdadvdgahirtllltffyrfmrplieagyvyiaqpptgykglgemnadqlwettmnpehrallqvkledaieadqtfemlmgdvvenrrqfiednavynernitsemresfldYamsvivaralpdvrdglkpvhrrilyglneqgmtpdksykksarivgdvmgkyhphgdSSiyeamvrmaqdfsyryplvdgqgnfgsmdgdgaaamRftearmtkitlellrdinkdtidfidnydgnerepsvlparfpnllangasgIavgmatnipphnltelingvlslsknpdisiaelmediegpdfptaglilgksgirrayetgrgsiqmrsravieergggrqrivvteipfqvnkarmiekiaelvrdkkidgitdlrdetslrtgvrvvidvrkdanasvilnnlykqtplqtsfgvnmialvngrpklinlkealvhylehqktvvrrrtqynlrkakdrahileglrialdhideiistiresdtdkvameslqqrfklsekqaqaildmrlrrltglerdkieaeynellnyiseletiladeevllqlvrdelteirdrfgddrrteiql > 7fvt_B interface=42,44,205,265,268,272,302,355, kladcsskspeeceiflvegdsaggstksgrdsrtqailplRgKilnvekarldrilnnneirqmitafgtgiggdfdlakaryhkivimtdadvdgahirtllltffyrfmrplieagyvyiaqpptgykglgemnadqlwettmnpehrallqvkledaieadqtfemlmgdvvenrrqfiednavynernitsemresfldYamsvivaralpdvrdglkpvhrrilyglneqgmtpdksykksarivgdvmgkyhphgdsSiyEamvRmaqdfsyryplvdgqgnfgsmdgdgaaamRftearmtkitlellrdinkdtidfidnydgnerepsvlparfpnllangasgIavgmatnipphnltelingvlslsknpdisiaelmediegpdfptaglilgksgirrayetgrgsiqmrsravieergggrqrivvteipfqvnkarmiekiaelvrdkkidgitdlrdetslrtgvrvvidvrkdanasvilnnlykqtplqtsfgvnmialvngrpklinlkealvhylehqktvvrrrtqynlrkakdrahileglrialdhideiistiresdtdkvameslqqrfklsekqaqaildmrlrrltglerdkieaeynellnyiseletiladeevllqlvrdelteirdrfgddrrteiqlg
interface signature	RKYSSRI/RKYSERRI

Estimated binding specificities ?

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# IC=10.537 IC/col=0.753 n_of_columns=14

specificity:

A |   0   0  24  21   9   0  24  24  21   0  44  96   0   0
C |  96   0  24   0   1   0  24  24  49  81  21   0  96   0
G |   0  96  24  31  86  96  24  24  11  15   7   0   0  96
T |   0   0  24  44   0   0  24  24  15   0  24   0   0   0

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updated Wed Sep 11 05:54:18 2024