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structure nameCRYO-EM STRUCTURE OF ROUS SARCOMA VIRUS CLEAVED SYNAPTIC COMPLEX (CSC) WITH HIV-1 INTEGRASE STRAND TRANSFER INHIBITOR MK-2048. CLUSTER IDENTIFIED BY 3-DIMENSIONAL VARIABILITY ANALYSIS IN CRYOSPARC.
sourceROUS SARCOMA VIRUS (STRAIN SCHMIDT-RUPPIN A) / ROUS SARCOMA VIRUS (STRAIN SCHMIDT-RUPPIN A) / ROUS SARCOMA VIRUS (STRAIN SCHMIDT-RUPPIN A) / ROUS SARCOMA VIRUS (STRAIN SCHMIDT-RUPPIN A)
experimentNMR
structural superfamilyRibonuclease H-like;DNA-binding domain of retroviral integrase;N-terminal Zn binding domain of HIV integrase;
reference complex7jn3_E
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureNQAERRER/TTQWRVW

Estimated binding specificities ?

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# IC=5.849 IC/col=0.975 n_of_columns=6 specificity:   
A |  13   0   0   0   0  13
C |  13   0   0   0   0  13
G |  13  96   0   0  96  13
T |  57   0  96  96   0  57
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updated Wed Sep 11 07:10:39 2024