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structure nameCRYO-EM STRUCTURE OF ROUS SARCOMA VIRUS CLEAVED SYNAPTIC COMPLEX (CSC) WITH HIV-1 INTEGRASE STRAND TRANSFER INHIBITOR MK-2048. CIC REGION OF A CLUSTER IDENTIFIED BY 3-DIMENSIONAL VARIABILITY ANALYSIS IN CRYOSPARC.
sourceROUS SARCOMA VIRUS (STRAIN SCHMIDT-RUPPIN A) / ROUS SARCOMA VIRUS (STRAIN SCHMIDT-RUPPIN A) / ROUS SARCOMA VIRUS (STRAIN SCHMIDT-RUPPIN A) / ROUS SARCOMA VIRUS (STRAIN SCHMIDT-RUPPIN A)
experimentNMR
structural superfamilyRibonuclease H-like;DNA-binding domain of retroviral integrase;N-terminal Zn binding domain of HIV integrase;
reference complex7jn3_E
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureQARRER/KIWTI

Estimated binding specificities ?

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# IC=3.929 IC/col=0.786 n_of_columns=5 specificity:   
A |  52   6  96  74   1
C |  14  78   0   7  92
G |  16   6   0   8   1
T |  14   6   0   7   2
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updated Sun Dec 15 07:37:02 2024