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structure nameCRYSTAL STRUCTURE OF TFAM (MITOCHONDRIAL TRANSCRIPTION FACTOR A) BRIDGING TWO NON-SEQUENCE SPECIFIC DNA SUBSTRATES
referenceGarcia-Diaz et al. 'Nucleic 50 322 2022
sourceHomo sapiens
experimentX-ray (resolution=2.84, R-factor=?)
structural superfamilyHMG-box;
reference complex7lbx_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSYLSKLTTIMKRYNVFPQLT/SYLSLTTIMKRYNVFPQL

Estimated binding specificities ?

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# IC=24.049 IC/col=0.587 n_of_columns=41 specificity:   
A |   0   0   0   1  24  24   0  24  24  24  24   0   0   0   1  24  24  24  11  24  24  24  24   1  96   0   0  24  24  24  24  65  24  24  90  96   0   1  24   1  82
C |  94  96   0   1  24  24   0  24  24  24  24   1  96   0  93  24  24  24   9  24  24  24  24   4   0   0  94  24  24  24  24   7  24  24   1   0   0   1  24   4   4
G |   2   0   0   1  24  24   0  24  24  24  24  94   0   0   1  24  24  24  63  24  24  24  24  90   0  96   2  24  24  24  24  13  24  24   4   0  96  93  24   1   9
T |   0   0  96  93  24  24  96  24  24  24  24   1   0  96   1  24  24  24  13  24  24  24  24   1   0   0   0  24  24  24  24  11  24  24   1   0   0   1  24  90   1
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updated Sun Dec 15 07:41:14 2024