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structure nameCRYSTAL STRUCTURE OF TFAM (MITOCHONDRIAL TRANSCRIPTION FACTOR A) BRIDGING TWO NON-SEQUENCE SPECIFIC DNA SUBSTRATES
referenceGarcia-Diaz et al. 'Nucleic 50 322 2022
sourceHomo sapiens
experimentX-ray (resolution=2.84, R-factor=?)
structural superfamilyHMG-box;
reference complex7lbx_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSYLSKLTTIMKRYNVFPQLT/SYLSLTTIMKRYNVFPQL

Estimated binding specificities ?

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# IC=20.822 IC/col=0.548 n_of_columns=38 specificity:   
A |   4   0   0   3  24  24   0  24  24  24  24   0   0   0   3  24  24  24   6  24  24  24  24   6  96   0   0  24  24  24  24  77  24  24  86  96   3   3
C |  86  96   0   4  24  24   0  24  24  24  24   6  96   0  87  24  24  24  10  24  24  24  24   3   0   0  89  24  24  24  24   7  24  24   4   0   3   0
G |   3   0   0   3  24  24   0  24  24  24  24  89   0   0   3  24  24  24  74  24  24  24  24  84   0  96   6  24  24  24  24   6  24  24   3   0  90  92
T |   3   0  96  86  24  24  96  24  24  24  24   1   0  96   3  24  24  24   6  24  24  24  24   3   0   0   1  24  24  24  24   6  24  24   3   0   0   1
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updated Thu Jul 31 13:33:51 2025