structure name | K. PNEUMONIAE TOPOISOMERASE IV (PARE-PARC) IN COMPLEX WITH DNA AND (3S)-10-[(3R)-3-(1-AMINOCYCLOPROPYL)PYRROLIDIN-1-YL]-9-FLUORO-3- METHYL-5-OXO-2,3-DIHYDRO-5H-[1,4]OXAZINO[2,3,4-IJ]QUINOLINE-6- CARBOXYLIC ACID (COMPOUND 25) |
reference | Bellamacina et al. J.Med.Chem. 64 6329 2021 |
experiment | X-ray (resolution=3.30, R-factor=0.284) |
structural superfamily | Type II DNA topoisomerase; |
sequence family | DNA gyrase/topoisomerase IV, subunit A; DNA gyrase B subunit, carboxyl terminus; |
multimeric complexes | 5eix_BJ 6waa_BD 6waa_FH 7lhz_AB |
reference complex | 6waa_D |
links to other resources | NAKB PDIdb DNAproDB |
protein sequence | |
interface signature | KRAEI |
Estimated binding specificities ?
readout + contact |
A | 54 0 57 0 96 C | 16 0 13 96 0 G | 13 0 13 0 0 T | 13 96 13 0 0scan! |
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updated Mon Dec 18 20:52:02 2023