interface graph thumbnail
legend  pdf

structure nameHSV1 POLYMERASE TERNARY COMPLEX WITH DSDNA AND PNU-183792
(DNA polymerase)
referenceHayes et al. 'Nat 12 3040 2021
sourceHuman herpesvirus 1
experimentX-ray (resolution=3.50, R-factor=0.227)
structural superfamilyDNA/RNA polymerases;Ribonuclease H-like;
sequence familyDNA polymerase family B; DNA polymerase family B, exonuclease do;
multimeric complexes8oj7_AB 8oja_AB 9enp_AB
reference complex8oja_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRKKRN

Estimated binding specificities ?

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# IC=3.576 IC/col=0.894 n_of_columns=4 specificity:   
A |  19  77   0   0
C |  19   0   0   0
G |  19   0  96  96
T |  39  19   0   0
scan!

Dendrogram of similar interfaces ?

matrix format

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updated Tue Dec 17 09:51:44 2024