interface graph thumbnail
legend  pdf

structure nameCYTOSINE-SPECIFIC METHYLTRANSFERASE HHAI/DNA COMPLEX
(CYTOSINE-SPECIFIC METHYLTRANSFERASE HHAI)
referenceRoberts et al. Nat.Struct.Biol. 5 872 1998
sourceHaemophilus haemolyticus
experimentX-ray (resolution=2.87, R-factor=0.156)
structural superfamilyS-adenosyl-L-methionine-dependent methyltransferases;
sequence familyC5 cytosinespecific DNA methylase;
reference complex5ciy_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureCISENVRRRQRN

Estimated binding specificities ?

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# IC=4.493 IC/col=1.123 n_of_columns=4 specificity:   
A |   0   0   0  70
C |  96   0  96   8
G |   0  96   0   8
T |   0   0   0  10
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updated Fri Jan 9 13:42:47 2026