7o56_AB : 3D-footprint complex

structure name	X-RAY STRUCTURE OF INTERFERON REGULATORY FACTOR 4 DNA BINDING DOMAIN BOUND TO AN INTERFERON-STIMULATED RESPONSE ELEMENT SOLVED BY PHOSPHORUS AND SULPHUR SAD METHODS
reference	Agnarelli et al. 'Acta 77 202 2021
source	Homo sapiens
experiment	X-ray (resolution=2.60, R-factor=?)
structural superfamily	"Winged helix" DNA-binding domain;
reference complex	7oot_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 7o56_A interface=75,78,79,83, ngklrqwlidqidsgkypglvweneeksifripwkhagkqdynreedaalfkawalfkgkfregidkpdpptwkTrlRCalnKsndfeelversqldisdpykvyrivpegakk > 7o56_B interface=74,75,77,78,79,82, gklrqwlidqidsgkypglvweneeksifripwkhagkqdynreedaalfkawalfkgkfregidkpdpptwkTRlRCAlnKsndfeelversqldisdpykvyrivpe
interface signature	TRCK/TRRCAK

Estimated binding specificities ?

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# IC=9.825 IC/col=0.893 n_of_columns=11

specificity:

A |  12   0  90   0  12   0  24   0  90   6   6
C |  12   0   0  96   6   0  24   0   0  90  12
G |  12   0   0   0  66  96  24   0   0   0  12
T |  60  96   6   0  12   0  24  96   6   0  66

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updated Sun Dec 15 11:30:34 2024