7o56_AB : 3D-footprint complex

structure name	X-RAY STRUCTURE OF INTERFERON REGULATORY FACTOR 4 DNA BINDING DOMAIN BOUND TO AN INTERFERON-STIMULATED RESPONSE ELEMENT SOLVED BY PHOSPHORUS AND SULPHUR SAD METHODS
reference	Agnarelli et al. 'Acta 77 202 2021
source	Homo sapiens
experiment	X-ray (resolution=2.60, R-factor=?)
structural superfamily	"Winged helix" DNA-binding domain;
reference complex	7oot_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 7o56_A interface=75,78,79,83, ngklrqwlidqidsgkypglvweneeksifripwkhagkqdynreedaalfkawalfkgkfregidkpdpptwkTrlRCalnKsndfeelversqldisdpykvyrivpegakk > 7o56_B interface=74,75,77,78,79,82, gklrqwlidqidsgkypglvweneeksifripwkhagkqdynreedaalfkawalfkgkfregidkpdpptwkTRlRCAlnKsndfeelversqldisdpykvyrivpe
interface signature	TRCK/TRRCAK

Estimated binding specificities ?

readout + contact

# IC=9.891 IC/col=0.899 n_of_columns=11

specificity:

A |  62   5   5  96  24   0  11   0   5  96  67
C |  13   0   1   0  24  96  67   0   0   0  16
G |  16  90   0   0  24   0   5  96   1   0   8
T |   5   1  90   0  24   0  13   0  90   0   5

scan!

home
updated Wed Sep 11 10:58:08 2024