7ox7_B : 3D-footprint complex

structure name	TARGET-BOUND SPCAS9 COMPLEX WITH TRAC CHIMERIC RNA-DNA GUIDE (CRISPR-associated endonuclease Cas9Csn1)
reference	van Overbeek et al. Mol.Cell 81 3637 2021
source	Streptococcus pyogenes serotype M1
experiment	X-ray (resolution=2.60, R-factor=0.210)
multimeric complexes	7v59_BE
reference complex	6vpc_F
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 7ox7_B interface=1072,1101,1184,1290,1292, kkysiglaigtnsvgwavitdeykvpskkfkvlgntdrhsikknligallfdsgetaeatrlkrtarrrytrrknricylqeifsnemakvddsffhrleesflveedkkherhpifgnivdevayhekyptiyhlrkklvdstdkadlrliylalahmikfrghfliegdlnpdnsdvdklfiqlvqtynqlfeenpinasgvdakailsarlsksrrlenliaqlpgekknglfgnlialslgltpnfksnfdlaedaklqlskdtydddldnllaqigdqyadlflaaknlsdaillsdilrvnteitkaplsasmikrydehhqdltllkalvrqqlpekykeiffdqskngyagyidggasqeefykfikpilekmdgteellvklnredllrkqrtfdngsiphqihlgelhailrrqedfypflkdnrekiekiltfripyyvgplargnsrfawmtrkseetitpwnfeevvdkgasaqsfiermtnfdknlpnekvlpkhsllyeyftvyneltkvkyvtegmrkpaflsgeqkkaivdllfktnrkvtvkqlkedyfkkiecfdsveisgvedrfnaslgtyhdllkiikdkdfldneenediledivltltlfedremieerlktyahlfddkvmkqlkrrrytgwgrlsrklingirdkqsgktildflksdgfanrnfmqlihddsltfkediqkaqvgdslhehianlagspaikkgilqtvkvvdelvkvmgrhkpeniviemarnsrermkrieegikelgsqilkehpventqlqneklylyylqngrdmyvdqeldinrlsdydvdaivpqsflkddsidnkvltrsdknrgksdnvpseevvkkmknywrqllnaklitqrkfdnltkaerlseldkagfikrqlvetrqitkhvaqildsrmntkydendklirevkvitlksklvsdfrkdfqfykvreinnyhhahdaylnavvgtalikkypklesefvygdykvatakyffysnimnffkteitlgeirkrplietngetgeivwdkgrdfatvrkvlsmpqvnivkktevqtggfsKesilpkrnsdkliarkkdwdpkkyggfdSptvaysvlvvakvekgkskklksvkellgitimerssfeknpidfleakgykevkkdliiklpkyslfelengrkrmlasagElqkgnelalpskyvnflylashydneqkqlfveqhkhyldeiieqisefskrviladanldkvlsaynkhrdkpireqaeniihlftltnlgapaafkyfdttidRkRytstkevldatlihqsitglyetridlsqlg
interface signature	KSERR

Estimated binding specificities ?

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# IC=3.569 IC/col=0.892 n_of_columns=4

specificity:

A |  38   0   0   0
C |  20  96  96  19
G |  19   0   0  77
T |  19   0   0   0

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updated Tue Dec 17 10:55:41 2024