interface graph thumbnail
legend  pdf

structure nameTARGET-BOUND SPCAS9 COMPLEX WITH TRAC FULL RNA GUIDE
(CRISPR-associated endonuclease Cas9Csn1)
referencevan Overbeek et al. Mol.Cell 81 3637 2021
sourceStreptococcus pyogenes serotype M1
experimentX-ray (resolution=2.75, R-factor=0.211)
multimeric complexes7v59_BE
reference complex6vpc_F
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKERR

Estimated binding specificities ?

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# IC=2.909 IC/col=0.727 n_of_columns=4 specificity:   
A |  42   5   0   7
C |  18  85  96   7
G |  18   3   0  75
T |  18   3   0   7
scan!

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updated Fri Sep 13 05:35:20 2024