interface graph thumbnail
legend  pdf

structure nameTARGET-BOUND SPCAS9 COMPLEX WITH AAVS1 CHIMERIC RNA-DNA GUIDE
(CRISPR-associated endonuclease Cas9Csn1)
referencevan Overbeek et al. Mol.Cell 81 3637 2021
sourceStreptococcus pyogenes serotype M1
experimentX-ray (resolution=2.15, R-factor=0.199)
multimeric complexes7v59_BE
reference complex6vpc_F
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKERR

Estimated binding specificities ?

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# IC=3.520 IC/col=0.880 n_of_columns=4 specificity:   
A |   0   0   0  19
C |   1   0   0  19
G |  19  96  96  20
T |  76   0   0  38
scan!

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updated Tue Dec 17 10:57:01 2024