7oxa_B : 3D-footprint complex

structure name	TARGET-BOUND SPCAS9 COMPLEX WITH AAVS1 CHIMERIC RNA-DNA GUIDE (CRISPR-associated endonuclease Cas9Csn1)
reference	van Overbeek et al. Mol.Cell 81 3637 2021
source	Streptococcus pyogenes serotype M1
experiment	X-ray (resolution=2.15, R-factor=0.199)
multimeric complexes	7v59_BE
reference complex	6vpc_F
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 7oxa_B interface=1068,1180,1286,1288, kkysiglaigtnsvgwavitdeykvpskkfkvlgntdrhsikknligallfdsgetaeatrlkrtarrrytrrknricylqeifsnemakvddsffhrleesflveedkkherhpifgnivdevayhekyptiyhlrkklvdstdkadlrliylalahmikfrghfliegdlnpdnsdvdklfiqlvqtynqlfeenpinasgvdakailsarlsksrrlenliaqlpgekknglfgnlialslgltpnfksnfdlaedaklqlskdtydddldnllaqigdqyadlflaaknlsdaillsdilrvnteitkaplsasmikrydehhqdltllkalvrqqlpekykeiffdqskngyagyidggasqeefykfikpilekmdgteellvklnredllrkqrtfdngsiphqihlgelhailrrqedfypflkdnrekiekiltfripyyvgplargnsrfawmtrkseetitpwnfeevvdkgasaqsfiermtnfdknlpnekvlpkhsllyeyftvyneltkvkyvtegmrkpaflsgeqkkaivdllfktnrkvtvkqlkedyfkkiecfdsveisgvedrfnaslgtyhdllkiikdkdfldneenediledivltltlfedremieerlktyahlfddkvmkqlkrrrytgwgrlsrklingirdkqsgktildflksdgfanrnfmqlihddsltfkediqkaqvgdslhehianlagspaikkgilqtvkvvdelvkvmgrhkpeniviemarnsrermkrieegikelsqilkehpntqlqneklylyylqngrdmyvdqeldinrlsdydvdaivpqsflkddsidnkvltrsdknrgksdnvpseevvkkmknywrqllnaklitqrkfdnltkaerlseldkagfikrqlvetrqitkhvaqildsrmntkydendklirevkvitlksklvsdfrkdfqfykvreinnyhhahdaylnavvgtalikkypklesefvygdykatakyffysnimnffkteitlgeirkrplietngetgeivwdkgrdfatvrkvlsmpqvnivkktevqtggfsKesilpkrnsdkliarkkdwdpkkyggfdsptvaysvlvvakvekgkskklksvkellgitimerssfeknpidfleakgykevkkdliiklpkyslfelengrkrmlasagElqkgnelalpskyvnflylashydneqkqlfveqhkhyldeiieqisefskrviladanldkvlsaynkhrdkpireqaeniihlftltnlgapaafkyfdttidRkRytstkevldatlihqsitglyetridlsqlgg
interface signature	KERR

Estimated binding specificities ?

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# IC=2.984 IC/col=0.746 n_of_columns=4

specificity:

A |  42   5   0  78
C |  18  85  96   6
G |  18   3   0   6
T |  18   3   0   6

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updated Fri Jan 9 14:51:42 2026