interface graph thumbnail
legend  pdf

structure nameSPCAS9 BOUND TO AAVS1 OFF-TARGET4 DNA SUBSTRATE
(CRISPR-associated endonuclease Cas9Csn1)
referencePacesa et al. Cell 185 4067 2022
sourceStreptococcus pyogenes
experimentX-ray (resolution=2.65, R-factor=0.192)
multimeric complexes7v59_BE
reference complex6vpc_F
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKERR

Estimated binding specificities ?

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# IC=3.061 IC/col=0.765 n_of_columns=4 specificity:   
A |   2   0   6  19
C |   2   0   6  19
G |   4  96  78  19
T |  88   0   6  39
scan!

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updated Fri Sep 13 07:18:23 2024