interface graph thumbnail
legend  pdf

structure nameSPCAS9 BOUND TO AAVS1 OFF-TARGET5 DNA SUBSTRATE
(CRISPR-associated endonuclease Cas9Csn1)
referencePacesa et al. Cell 185 4067 2022
sourceStreptococcus pyogenes
experimentX-ray (resolution=2.75, R-factor=0.191)
multimeric complexes7v59_BE
reference complex6vpc_F
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKERR

Estimated binding specificities ?

contactlogo
# IC=3.232 IC/col=0.808 n_of_columns=4 specificity:   
A |   2   0   4  16
C |   2   0   4  16
G |   4  96  81  16
T |  88   0   7  48
scan!

home
updated Sat Aug 2 20:01:57 2025