interface graph thumbnail
legend  pdf

structure nameSPCAS9 BOUND TO FANCF ON-TARGET DNA SUBSTRATE
(CRISPR-associated endonuclease Cas9Csn1)
referencePacesa et al. Cell 185 4067 2022
sourceStreptococcus pyogenes
experimentX-ray (resolution=2.40, R-factor=0.199)
multimeric complexes7v59_BE
reference complex6vpc_F
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKSERR

Estimated binding specificities ?

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# IC=2.736 IC/col=0.684 n_of_columns=4 specificity:   
A |   3   0   9  18
C |   3   0   9  18
G |   5  96  67  18
T |  85   0  11  42
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updated Fri Jan 9 17:08:50 2026