interface graph thumbnail
legend  pdf

structure nameSPCAS9 BOUND TO FANCF OFF-TARGET1 DNA SUBSTRATE
(CRISPR-associated endonuclease Cas9Csn1)
referencePacesa et al. Cell 185 4067 2022
sourceStreptococcus pyogenes
experimentX-ray (resolution=2.50, R-factor=0.205)
multimeric complexes7v59_BE
reference complex6vpc_F
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKSERR

Estimated binding specificities ?

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# IC=2.374 IC/col=0.593 n_of_columns=4 specificity:   
A |  67   0   8  16
C |   9   0   8  16
G |  11  96  70  19
T |   9   0  10  45
scan!

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updated Mon Jun 29 02:33:45 2026