interface graph thumbnail
legend  pdf

structure nameSPCAS9 BOUND TO FANCF OFF-TARGET2 DNA SUBSTRATE
(CRISPR-associated endonuclease Cas9Csn1)
referencePacesa et al. Cell 185 4067 2022
sourceStreptococcus pyogenes
experimentX-ray (resolution=2.45, R-factor=0.204)
multimeric complexes7v59_BE
reference complex6vpc_F
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKSERR

Estimated binding specificities ?

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# IC=2.433 IC/col=0.608 n_of_columns=4 specificity:   
A |  42   8   0   9
C |  18  74  96   9
G |  18   7   0  11
T |  18   7   0  67
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updated Tue Dec 17 12:46:53 2024