interface graph thumbnail
legend  pdf

structure nameSPCAS9 BOUND TO FANCF OFF-TARGET3 DNA SUBSTRATE
(CRISPR-associated endonuclease Cas9Csn1)
referencePacesa et al. Cell 185 4067 2022
sourceStreptococcus pyogenes
experimentX-ray (resolution=2.25, R-factor=0.197)
multimeric complexes7v59_BE
reference complex6vpc_F
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKSERR

Estimated binding specificities ?

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# IC=3.142 IC/col=0.786 n_of_columns=4 specificity:   
A |  57   0   0  13
C |  13  96  96  13
G |  13   0   0  54
T |  13   0   0  16
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updated Sat Aug 2 20:03:50 2025