interface graph thumbnail
legend  pdf

structure nameSPCAS9 BOUND TO FANCF OFF-TARGET7 DNA SUBSTRATE
(CRISPR-associated endonuclease Cas9Csn1)
referencePacesa et al. Cell 185 4067 2022
sourceStreptococcus pyogenes
experimentX-ray (resolution=2.25, R-factor=0.218)
multimeric complexes7v59_BE
reference complex6vpc_F
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKERR

Estimated binding specificities ?

readout + contactlogo
# IC=2.433 IC/col=0.608 n_of_columns=4 specificity:   
A |  67   0   7  18
C |   9   0   7  18
G |  11  96  74  18
T |   9   0   8  42
scan!

home
updated Sat Aug 2 20:05:14 2025